Koi Cream is not intended to from a seal or barrier, like G7, but to denature proteins that inhibit healing it is antiseptic and anti-inflammatory. It can be applied to skin lesions of all types alone or over Aquatec. When a wound starts to heal discontinue all other products using only Koi cream. Instead of sedating a fish for a fuller treatment it can be applied to lesions alone or over Aquatec and this can be carried out with the fish in the net. Koi cream can be applied as often as the fish will tolerate the stress of netting.